31 August 2016

Media discussion: ”Your Body, Your Life, Your Choice” – Acne caused by hyperandrogen and its effect on women

  • Hyperandrogen is a medical condition characterized by excessive levels of androgens in the body, which affects 10 - 20% of reproductive-age women1.
  • Women require 1% androgen hormone in their bodies2 and anything more may lead to health problems including medium to severe acne.
  • Acne problems caused by hyperandrogen may be treated with combined oral contraceptives which has strong antiandrogenic effect3.
  • 18% of clinically important depression and 44% of anxiety have been reported among acne patients4.
  • Acne treatment represents 18% of overall worldwide cost for the treatment of skin disease5.

Jakarta, 31 August 2016 – As the Life Science Company, Bayer Indonesia is committed to help Indonesians achieve a better quality of life through public education and awareness on health issues and topics. Today on 31 August 2016, Bayer is conducting a media discussion with the theme of “Your Body, Your Life,Your Choice: Acne caused by hyperandrogen and its effect for women”. During this discussion, Bayer Indonesia is bringing the topic forth along with potential therapies that are available for patients that can help them overcome this problem.

Estrogen, progesterone and androgen hormones in women’s bodies have specific health functions. The hormone influencing skin condition and hair growth is androgen. Studies show that hyperandrogen, a medical condition characterized by excessive levels of androgens in the body, affects 10-20%6  of reproductive-age women. Healthy women require 1% androgen hormone in their bodies7 and anything more may lead to health problems including medium to severe acne.

dr. Suksmagita Pratidina, Sp.KK, “Acne occurs when hair follicles become clogged with dead skin cells caused by excessive sebum / greasy skin. This condition may be caused by excessive unbound androgen hormone as it stimulates oil gland and sebum activities that can cause a smooth and soft facial skin to become greasy with acne and comedone. Acne is commonly classified by severity as mild, moderate, or severe and acne caused by hyperandrogen are in the moderate to severe ranges”.

Dr.dr. Budi Wiweko,SpOG(K) said, “Hyperandrogen is a hormonal imbalance in women, and it can lead to serious health problems such as moderate to severe acne. Studies have shown that women with hyperandrogen will have clinical symptoms such as Seborrhea (skin inflammation that can lead to scarring and may cause psychological and social problems), Acne, Hirsutism (excessive body hair in women on parts of the body where hair is normally absent or minimal, such as on the chin or chest), Alopecia (hair loss or baldness) or irregular menstrual cycle often referred as SAHA syndrome, or also known as dermatological androgenization syndrome, which is a medical syndrome characterized by seborrhoea, acne, hirsutism and alopecia. Acne problems caused by hyperandrogen may be treated with combined oral contraceptives that contain cyproterone acetate, which has strong antiandrogenic effect.

dr. Suksmagita Pratidina, Sp.KK added, ”Skin problems caused by hygiene factors are easier to treat as all a patient needs to do is keep her skin clean to clear up her acne. Acne caused by hyperandrogen however is different and various treatment or therapy that patients apply would not be effective to treat it unless the source of the problem is addressed appropriately.”

Acne can cause adverse emotional effects to women leading to various psychological symptoms such as poor self-esteem, poor confidence, poor self-image and anger. 18% of clinically important depression and 44% of anxiety8 have been reported among acne patients while 6% of patients have even reported suicidal ideation9. Moreover, acne treatment represents 18.3% of overall worldwide cost for the treatment of skin disease10.

Every woman deserves to have access to proper education on the matter and to seek correct information on hyperandrogen as a medical condition that affects skin health. Bayer Indonesia has 25 years in proven experience in helping Indonesian women attain a better quality of life by means of healthy skin, free of acne problems caused by hyperandrogen.

 

Bayer: Science For A Better Life

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At the same time, the Group aims to create value through innovation, growth and high earning power. Bayer is committed to the principles of sustainable development and to its social and ethical responsibilities as a corporate citizen. In fiscal 2015, the Group employed around 117,000 people and had sales of EUR 46.3 billion. Capital expenditures amounted to EUR 2.6 billion, R&D expenses to EUR 4.3 billion. These figures include those for the high-tech polymers business, which was floated on the stock market as an independent company named Covestro on October 6, 2015. For more information, go to www.bayer.com.

 

Media Contact:

Anton Susanto

Head of Communications PT Bayer Indonesia

Phone: +62-21-30491506

E-mail: anton.susanto@bayer.com

 

Forward-Looking Statements

This news release may contain forward-looking statements based on current assumptions and forecasts made by Bayer management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments.

 

Reference:

  1. Redmond GP. Int J Fertil Womens Med 1998; 43 91-97.
  2. Speroff, Leon et.al.Clinical Gynecologic Endocrinology and Infertility 6th edition.1999: 21
  3. Muhn et al. Ann NY Acad Sci. 1995;761:311–35;
  4. Yeung CK et al. Acta Derm Venereol 2002; 82: 104–107.
  5. ChenW, Thiboutot D, Zouboulis CC. Cutaneous androgen metabolism: Basic research and clinical perspectives. J Invest Dermatol 2002; 119:992-1007.
  6. Redmond GP. Int J Fertil Womens Med 1998; 43 91-97.
  7. Speroff, Leon et.al.Clinical Gynecologic Endocrinology and Infertility 6th edition.1999: 21
  8. Kellet SC and Gawkrodger DJ. Br. J Dematol 1999; 273-282
  9. Gupta MA and Gupta AK. Br J Dematol 1998; 139: 846-850
  10. ChenW, Thiboutot D, Zouboulis CC. Cutaneous androgen metabolism: Basic research and clinical perspectives. J Invest Dermatol 2002; 119:992-1007.

 

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